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CONTACT A REP
Interested in connecting with an ANI Pharmaceuticals representative?

Fill out the request form below if you wish to be contacted with more information on Cortrophin Gel.

This form is for healthcare professionals only. If you are a patient looking to contact customer service, please call 1-800-434-1121 or email info@anipharmaceuticals.com.

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Helping patients access Cortrophin Gel

ANI Pharmaceuticals is committed to expanding patient access to Cortrophin Gel and to lowering the cost of ACTH therapy.* Most eligible commercially insured patients can pay as little as $0.†

The Cortrophin In Your Corner program‡ is here to help your patients figure out what coverage and financial support options are available to them.

*23.2% discount is based on the 5-mL vial and is relative to the average price for the existing therapy option within the ACTH class. WAC price for Acthar® Gel is $9,332.60 per mL; WAC price for Cortrophin Gel is $7,169.80 per mL (date: January 2026). Sources: IBM Micromedex® RED BOOK® and Keenova Therapeutics. Our Product Pricing. Acthar® Gel. Accessed March 2026. https://www.keenova.com/products-and-capabilities/product-pricing/

†Restrictions, limitations, and/or eligibility requirements apply. The maximum financial assistance provided to eligible patients is $25,000 per calendar year. The patient will be responsible for any remaining out-of-pocket costs for Cortrophin Gel for that calendar year.

‡Not all patients will be eligible for all services offered by Cortrophin In Your Corner.

Cortrophin In Your Corner

—A dedicated support program‡ that is designed to help your patients throughout the treatment process

Resource icon

Get access to useful resources

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A dedicated Nurse Access Specialist§ may help them navigate the treatment process and facilitate additional injection training

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Connect with a support center that is available to answer questions and provide educational information

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Obtain information on insurance coverage and financial support, including copay assistance

Resource icon

Coordinate shipments with the specialty pharmacy supplying their medication (if applicable)

Question markQuestions?

Call us at 1-800-805-5258
Monday-Friday, 8 AM-8 PM ET

Resource icon

Get access to useful resources

Resource icon

Obtain information on insurance coverage and financial support, including copay assistance

Resource icon

A dedicated Nurse Access Specialist§ may help them navigate the treatment process and facilitate additional injection training

Resource icon

Coordinate shipments with the specialty pharmacy supplying their medication (if applicable)

Resource icon

Connect with a support center that is available to answer questions and provide educational information

Question markQuestions?

Call us at 1-800-805-5258
Monday-Friday, 8 AM-8 PM ET

‡Not all patients will be eligible for all services offered by Cortrophin In Your Corner.

§Nurse Access Specialists do not give medical advice and will direct patients to a healthcare professional for any treatment-related questions.

Savings card

A lower-cost ACTH treatment option for patients in need of ACTH therapy

See patient eligibility

commercial plans iconFor patients with commercial insurance plans

Cortrophin In Your Corner can help eligible, commercially insured patients get their medication for as little as $0 per prescription fill, if receiving through a pharmacy.† The Copay Savings Program is for approved indications only. Patients can sign up for Cortrophin In Your Corner at www.cortrophin.com/copay-sign-up/, or they’ll be automatically enrolled upon completion of the enrollment form. Copay assistance may also be available if administering Cortrophin Gel in your office.

†Restrictions, limitations, and/or eligibility requirements apply. The maximum financial assistance provided to eligible patients is $25,000 per calendar year. The patient will be responsible for any remaining out-of-pocket costs for Cortrophin Gel for that calendar year.

SEE FULL TERMS AND CONDITIONS

commercial plans iconFor patients with government insurance plans

Patients may be eligible for financial support through an independent foundation.

commercial plans iconFor patients with limited or no insurance

If your patient lacks insurance and meets certain financial requirements, they may be eligible for the ANI Pharmaceuticals Patient Assistance Program.

If they wish to apply for the Patient Assistance Program (PAP), have them download and fill out the application below. Once completed, they can mail or fax the application in to see if they qualify for the Patient Assistance Program.

download PAP Application
Prescribing
Cortrophin Gel

Access important
enrollment information.

Prescribe & Enroll
About Cortrophin Gel & Dosing

Learn more about Cortrophin Gel and view recommended dosing by indication.

Learn More
Provider & Patient
Resources

Explore downloadable resources, as well as educational materials for your appropriate patients, including injection guides.

Get Resources

References: 1. IBM Micromedex® RED BOOK. 2. Keenova Therapeutics. Our Product Pricing. Acthar® Gel. Accessed March 13, 2026. https://www.keenova.com/products-and-capabilities/product-pricing/

Indications
Important Safety Information
Expand ISI
IndicationsExpand ISI

Cortrophin Gel is a prescription medicine that is injected subcutaneously or intramuscularly. It is indicated for:

Cortrophin Gel is indicated for:

  • Acute exacerbations of multiple sclerosis.
  • Short-term administration as an adjunctive therapy during an acute episode or exacerbation in rheumatoid arthritis, including juvenile rheumatoid arthritis; psoriatic arthritis; ankylosing spondylitis; and acute gouty arthritis.
  • Exacerbations or as maintenance therapy in select cases of systemic lupus erythematosus and systemic dermatomyositis (polymyositis).
  • Severe erythema multiforme (Stevens-Johnson syndrome) and severe psoriasis.
  • Atopic dermatitis and serum sickness.
  • Severe acute and chronic allergic and inflammatory conditions affecting the eye and its adnexa, such as allergic conjunctivitis, keratitis, iritis and iridocyclitis, diffuse posterior uveitis and choroiditis, optic neuritis, chorioretinitis, and anterior segment inflammation.
  • Symptomatic sarcoidosis.
  • Inducing a diuresis or remission of proteinuria due to nephrotic syndrome without uremia of the idiopathic type or that due to lupus erythematosus.
Important Safety InformationExpand ISI
Contraindications
  • Cortrophin Gel is contraindicated for intravenous administration.
  • Cortrophin Gel is contraindicated in patients who have any of the following conditions: scleroderma; osteoporosis; systemic fungal infections; ocular herpes simplex; recent surgery; history of or the presence of a peptic ulcer; congestive heart failure; hypertension; primary adrenocortical insufficiency; adrenocortical hyperfunction; or sensitivity to proteins derived from porcine sources.
Warnings and Precautions
  • Infections: Corticotropin therapy may increase susceptibility to infections and may mask the symptoms of infections.
  • Adrenal insufficiency: Prolonged corticotropin therapy can increase the potential for adrenal insufficiency after withdrawal of the medication. Adrenal insufficiency may be minimized by gradually reducing the corticotropin dosage. Hormone therapy should be reinstituted if stressful situations arise during discontinuation.
  • Elevated blood pressure, salt and water retention, and hypokalemia: Corticotropin can cause elevation of blood pressure, salt and water retention, and increased excretion of potassium or calcium.
  • Masking symptoms of other diseases: Corticotropin may only suppress signs and symptoms of chronic disease without altering the natural course of disease.
  • Psychiatric reactions: Psychic derangements may appear when corticotropin is used, ranging from euphoria, insomnia, mood swings, personality changes, and depression to psychosis. Existing conditions may be aggravated.
  • Ophthalmic reactions: Prolonged use of corticotropin may produce posterior subcapsular cataracts and glaucoma with possible damage to the optic nerves.
  • Immunogenicity potential: Prolonged administration of Cortrophin Gel may increase the risk of hypersensitivity reactions. Cases of anaphylaxis have been reported in the postmarketing setting. Neutralizing antibodies with chronic administration may lead to loss of endogenous ACTH and Cortrophin Gel activity.
  • Vaccination: Patients should not be vaccinated against smallpox while on corticotropin therapy. Other immunizations should be undertaken with caution due to possible neurologic complications and lack of antibody response.
  • Use in patients with hypothyroidism and cirrhosis: There is an enhanced effect in patients with hypothyroidism and in those with cirrhosis.
  • Use in patients with latent tuberculosis or tuberculin reactivity: Closely observe for reactivation of the disease.
  • Comorbid diseases: Corticotropin should be used with caution in patients with diabetes, abscess, pyogenic infections, diverticulitis, renal insufficiency, and myasthenia gravis.
  • Growth and development: Carefully observe growth and development of infants and children on prolonged corticotropin therapy.
  • Acute gouty arthritis: Treatment of acute gouty arthritis should be limited to a few days. Conventional concomitant therapy should be administered during corticotropin treatment and for several days after it is stopped.
  • Drug interactions: Aspirin should be used cautiously with corticotropin in hypoprothrombinemia.
  • Pregnancy: Since fetal abnormalities have been observed in animals, Cortrophin Gel should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
Adverse Reactions

Adverse reactions for Cortrophin Gel include fluid or sodium retention; muscle weakness; osteoporosis; peptic ulcer with possible perforation and hemorrhage; injection site reactions; impaired wound healing; hypertension; convulsions; headache; development of Cushingoid state; suppression of growth in children; anaphylaxis (anaphylactic shock, urticaria, respiratory compromise, edema); and weight gain. These are not all the adverse reactions reported with Cortrophin Gel.

Please see full Prescribing Information.

Indications

Cortrophin Gel is a prescription medicine that is injected subcutaneously or intramuscularly. It is indicated for:

Cortrophin Gel is indicated for:

  • Acute exacerbations of multiple sclerosis.
  • Short-term administration as an adjunctive therapy during an acute episode or exacerbation in rheumatoid arthritis, including juvenile rheumatoid arthritis; psoriatic arthritis; ankylosing spondylitis; and acute gouty arthritis.
  • Exacerbations or as maintenance therapy in select cases of systemic lupus erythematosus and systemic dermatomyositis (polymyositis).
  • Severe erythema multiforme (Stevens-Johnson syndrome) and severe psoriasis.
  • Atopic dermatitis and serum sickness.
  • Severe acute and chronic allergic and inflammatory conditions affecting the eye and its adnexa, such as allergic conjunctivitis, keratitis, iritis and iridocyclitis, diffuse posterior uveitis and choroiditis, optic neuritis, chorioretinitis, and anterior segment inflammation.
  • Symptomatic sarcoidosis.
  • Inducing a diuresis or remission of proteinuria due to nephrotic syndrome without uremia of the idiopathic type or that due to lupus erythematosus.
Important Safety InformationContraindications
  • Cortrophin Gel is contraindicated for intravenous administration.
  • Cortrophin Gel is contraindicated in patients who have any of the following conditions: scleroderma; osteoporosis; systemic fungal infections; ocular herpes simplex; recent surgery; history of or the presence of a peptic ulcer; congestive heart failure; hypertension; primary adrenocortical insufficiency; adrenocortical hyperfunction; or sensitivity to proteins derived from porcine sources.
Warnings and Precautions
  • Infections: Corticotropin therapy may increase susceptibility to infections and may mask the symptoms of infections.
  • Adrenal insufficiency: Prolonged corticotropin therapy can increase the potential for adrenal insufficiency after withdrawal of the medication. Adrenal insufficiency may be minimized by gradually reducing the corticotropin dosage. Hormone therapy should be reinstituted if stressful situations arise during discontinuation.
  • Elevated blood pressure, salt and water retention, and hypokalemia: Corticotropin can cause elevation of blood pressure, salt and water retention, and increased excretion of potassium or calcium.
  • Masking symptoms of other diseases: Corticotropin may only suppress signs and symptoms of chronic disease without altering the natural course of disease.
  • Psychiatric reactions: Psychic derangements may appear when corticotropin is used, ranging from euphoria, insomnia, mood swings, personality changes, and depression to psychosis. Existing conditions may be aggravated.
  • Ophthalmic reactions: Prolonged use of corticotropin may produce posterior subcapsular cataracts and glaucoma with possible damage to the optic nerves.
  • Immunogenicity potential: Prolonged administration of Cortrophin Gel may increase the risk of hypersensitivity reactions. Cases of anaphylaxis have been reported in the postmarketing setting. Neutralizing antibodies with chronic administration may lead to loss of endogenous ACTH and Cortrophin Gel activity.
  • Vaccination: Patients should not be vaccinated against smallpox while on corticotropin therapy. Other immunizations should be undertaken with caution due to possible neurologic complications and lack of antibody response.
  • Use in patients with hypothyroidism and cirrhosis: There is an enhanced effect in patients with hypothyroidism and in those with cirrhosis.
  • Use in patients with latent tuberculosis or tuberculin reactivity: Closely observe for reactivation of the disease.
  • Comorbid diseases: Corticotropin should be used with caution in patients with diabetes, abscess, pyogenic infections, diverticulitis, renal insufficiency, and myasthenia gravis.
  • Growth and development: Carefully observe growth and development of infants and children on prolonged corticotropin therapy.
  • Acute gouty arthritis: Treatment of acute gouty arthritis should be limited to a few days. Conventional concomitant therapy should be administered during corticotropin treatment and for several days after it is stopped.
  • Drug interactions: Aspirin should be used cautiously with corticotropin in hypoprothrombinemia.
  • Pregnancy: Since fetal abnormalities have been observed in animals, Cortrophin Gel should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
Adverse Reactions

Adverse reactions for Cortrophin Gel include fluid or sodium retention; muscle weakness; osteoporosis; peptic ulcer with possible perforation and hemorrhage; injection site reactions; impaired wound healing; hypertension; convulsions; headache; development of Cushingoid state; suppression of growth in children; anaphylaxis (anaphylactic shock, urticaria, respiratory compromise, edema); and weight gain. These are not all the adverse reactions reported with Cortrophin Gel.

Please see full Prescribing Information.